SCHEMBL75600

SCHEMBL75600

c1ccc(-c2ccc3ccccc3c2Nc2nc(Nc3c(-c4ccccc4)ccc4ccccc34)nc(Nc3c(-c4ccccc4)ccc4ccccc34)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.40
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 4/20 0.40
HPGD P15428 4/20 0.40
TSHR P16473 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TP53 P04637 3/20 0.39
MAPK1 P28482 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TNF P01375 1/20 0.39
CYP2A6 P11509 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15400423 0.89 ALDH1A1 (0.44) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL23780947 0.85 ALDH1A1 (0.41) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL4979017 0.84 HSD17B10 (0.48) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL15399698 0.81 CDC25B (0.49) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL4232444 0.79 ALDH1A1 (0.42) MAPTALDH1A1HPGDTSHRHSD17B10
SCHEMBL27937819 0.78 HSD11B1 (0.46) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL7862553 0.77 KDM1A (0.55) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL11710361 0.77 ALDH1A1 (0.39) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL6405547 0.77 ABCG2 (0.48) MAPTALDH1A1KDM4EHPGDTSHR
SCHEMBL15511194 0.76 ALDH1A1 (0.33) MAPTALDH1A1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110240965-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-10-06 US claimed
US-7597967-B2 Phosphorescent OLEDs with exciton blocking layer EASTMAN KODAK COMPANY (US) 2009-10-06 US claimed
EP-1701394-A1 Organic electroluminescent device and method of manufacturing the same Samsung SDI Co., Ltd. (KR) 2006-09-13 EP claimed
US-20060199038-A1 Organic electroluminescent device and method of manufacturing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2006-09-07 US claimed
US-20060134461-A1 Organometallic materials and electroluminescent devices EASTMAN KODAK COMPANY 2006-06-22 US claimed
US-20060134460-A1 Phosphorescent oleds with exciton blocking layer GLOBAL OLED TECHNOLOGY LLC 2006-06-22 US claimed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US claimed
US-20050287393-A1 Organic electroluminescent device SAMSUNG SDI CO., LTD. (KR) 2005-12-29 US claimed
EP-1610398-A2 Organic electroluminescent device Samsung SDI Co., Ltd. (KR) 2005-12-28 EP claimed
EP-2984079-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2020-07-01 EP disclosed
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices POWER OLEDS LIMITED (GB) 2019-10-08 US disclosed
EP-2243177-B1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC (US) 2019-05-15 EP disclosed
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2018-11-08 US disclosed
EP-2396801-B1 OLED DEVICE WITH FLUORANTHENE-MACROCYCLIC MATERIALS GLOBAL OLED TECHNOLOGY LLC (US) 2018-05-23 EP disclosed
US-20060199038-A1 Organic electroluminescent device and method of manufacturing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2006-09-07 US disclosed
US-20060134461-A1 Organometallic materials and electroluminescent devices EASTMAN KODAK COMPANY 2006-06-22 US disclosed
US-20060134460-A1 Phosphorescent oleds with exciton blocking layer GLOBAL OLED TECHNOLOGY LLC 2006-06-22 US disclosed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US disclosed
US-20050287393-A1 Organic electroluminescent device SAMSUNG SDI CO., LTD. (KR) 2005-12-29 US disclosed
EP-1610398-A2 Organic electroluminescent device Samsung SDI Co., Ltd. (KR) 2005-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 MAPT 1775/4885ALDH1A1 789/4885KDM4E 4166/4885
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices NAT1, SLCO2A1, SLCO2B1 MAPT 1775/4885ALDH1A1 789/4885KDM4E 4166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.