Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.47 |
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.46 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.41 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524025 | 0.89 | LMNA (0.52) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5527592 | 0.86 | CTSL (0.50) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5529192 | 0.83 | HPGD (0.56) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5526372 | 0.82 | MEN1 (0.55) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5529768 | 0.81 | CTSL (0.65) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6021764 | 0.80 | CTSL (0.64) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5517750 | 0.80 | CTSL (0.64) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL6020007 | 0.80 | CTSL (0.51) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL7552956 | 0.80 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL7472684 | 0.80 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000055125-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |