Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 15/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463679 | 0.92 | HRH4 (0.56) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL4309930 | 0.92 | HRH4 (0.50) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL4309987 | 0.84 | HRH4 (0.50) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL4318596 | 0.79 | HRH4 (0.47) | HRH4MEN1POLBKMT2AHTR3A | |
| SCHEMBL6046294 | 0.77 | HTR6 (0.43) | — | |
| SCHEMBL4313461 | 0.76 | ADRB1 (0.38) | TSHR | |
| SCHEMBL4315093 | 0.73 | TSHR (0.73) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL24969772 | 0.72 | HRH4 (0.70) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL30223071 | 0.72 | HRH4 (0.70) | HRH4MEN1POLBKMT2ATSHR | |
| SCHEMBL4308805 | 0.72 | TSHR (0.60) | HRH4MEN1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |