Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TCF4 | P15884 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372302 | 0.97 | CA2 (0.39) | CA2CA4POLBCA1CA9 | |
| Zinc Ion SCHEMBL28885471 | 0.97 | CA2 (0.39) | CA2CA4POLBCA1CA9 | |
| SCHEMBL448024 | 0.97 | CA2 (0.44) | CA2CA4POLBCA1CA9 | |
| SCHEMBL1683498 | 0.97 | CA2 (0.39) | CA2CA4POLBCA1CA9 | |
| SCHEMBL6679381 | 0.89 | POLB (0.43) | CA2POLBCA1CA9CA12 | |
| SCHEMBL9440690 | 0.82 | LTB4R (0.39) | — | |
| SCHEMBL1269299 | 0.82 | CA1 (0.47) | CA2CA1CA9CA12 | |
| SCHEMBL1683497 | 0.81 | CA1 (0.46) | CA2CA1CA9CA12 | |
| SCHEMBL27578522 | 0.81 | POLB (0.57) | CA2POLBCA1CA9CA12 | |
| Ammonia Solution, Strong SCHEMBL26113186 | 0.81 | CA1 (0.46) | CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788914-B | The polyester-polyamide blends of good color are kept under heat treatment | M&G 美国有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-104788914-A | Polyester-polymer blends maintaining good color under thermal treatment | M & G POLIMERI ITALIA SPA | 2015-07-22 | — | — | CN | disclosed |
| EP-2181152-B1 | PHOSPHITE STABILIZERS FOR IONOMERIC POLYESTER COMPOUNDS | M & G POLIMERI ITALIA SPA (IT) | 2013-10-30 | — | — | EP | disclosed |
| EP-2264543-B1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORP (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8063124-B2 | Phosphite stabilizers for ionomeric polyester compounds | M&G USA CORPORATION (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110057349-A1 | PHOSPHITE STABILIZERS FOR IONOMERIC POLYESTER COMPOUNDS | M&G USA CORPORATION | 2011-03-10 | — | — | US | disclosed |
| EP-2264543-A1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | Xerox Corporation (US) | 2010-12-22 | — | — | EP | disclosed |
| CN-101784606-A | Polyester-polyamide blends that maintain good color under heat treatment | M & G POLIMERI ITALIA SPA | 2010-07-21 | — | — | CN | disclosed |
| CN-101784598-A | Phosphite Stabilizers for Ionic Polyester Compounds | M & G POLIMERI ITALIA SPA | 2010-07-21 | — | — | CN | disclosed |
| EP-2181152-A1 | PHOSPHITE STABILIZERS FOR IONOMERIC POLYESTER COMPOUNDS | M & G Polimeri Italia S.P.A. (IT) | 2010-05-05 | — | — | EP | disclosed |
| US-20090054567-A1 | PHOSPHITE STABILIZERS FOR IONOMERIC POLYESTER COMPOUNDS | M&G USA CORPORATION | 2009-02-26 | — | — | US | disclosed |
| WO-2009026555-A1 | PHOSPHITE STABILIZERS FOR IONOMERIC POLYESTER COMPOUNDS | M & G POLIMERI ITALIA S.P.A. (IT) | 2009-02-26 | — | — | WO | disclosed |
| US-7312011-B2 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1684124-A2 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | Xerox Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20060160010-A1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORPORATION (US) | 2006-07-20 | — | — | US | disclosed |