SCHEMBL7560179

SCHEMBL7560179

Cc1cc(C(=O)NCc2cc(C(=N)N)ccc2O)ccc1N(C(=O)CCN)C1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.38
PRSS1 P07477 3/20 0.38
EPHX2 P34913 2/20 0.38
F2 P00734 5/20 0.38
KLKB1 P03952 7/20 0.38
PLG P00747 1/20 0.36
PROC P04070 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7584891 0.99 F10 (0.38) F10PRSS1EPHX2F2KLKB1
SCHEMBL7561457 0.94 F10 (0.40) F10PRSS1EPHX2F2KLKB1
Hydrochloric Acid SCHEMBL7563518 0.93 F10 (0.39) F10PRSS1EPHX2F2KLKB1
SCHEMBL6554459 0.92 F10 (0.40) F10PRSS1EPHX2F2KLKB1
Hydrochloric Acid SCHEMBL6555877 0.92 F10 (0.39) F10PRSS1EPHX2F2KLKB1
SCHEMBL6556891 0.90 F2 (0.39) F10PRSS1EPHX2F2KLKB1
Hydrochloric Acid SCHEMBL6554847 0.89 F2 (0.39) F10PRSS1EPHX2F2KLKB1
SCHEMBL6555900 0.88 F10 (0.41) F10PRSS1EPHX2F2KLKB1
SCHEMBL6554523 0.86 F10 (0.42) F10PRSS1EPHX2F2KLKB1
Hydrochloric Acid SCHEMBL6555866 0.85 F10 (0.41) F10PRSS1EPHX2F2KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US claimed
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151534-A1 Antithrombotic compounds SERPINC1, PF4, F2 F10 35/4885PRSS1 776/4885EPHX2 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.