SCHEMBL7560188

SCHEMBL7560188

CCCC(CCC(F)F)CO[C]=O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342662 0.88 CA12 (0.45) CA12CA1CA2CA7CA14
SCHEMBL3040106 0.80 CYP3A4 (0.41) CA12CA1CA2CA7CA14
SCHEMBL8794021 0.79 CYP3A4 (0.39) CA12CA1CA2CA7CA14
SCHEMBL5739082 0.78 LMNA (0.39) CA12CA1CA2CA7CA14
SCHEMBL1722350 0.75
SCHEMBL3040097 0.74 CA12 (0.34) CA12CA1CA2CA7CA14
SCHEMBL9555140 0.74 CA12 (0.34) CA12CA1CA2CA7CA14
SCHEMBL8634225 0.74 LMNA (0.41) CA1
SCHEMBL9712790 0.73 CA12 (0.31) CA12CA1CA2CA7CA14
SCHEMBL7204580 0.72 LMNA (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187819-A1 N-SUBSTITUTED PERHYDRO DIAZINE BASF AKTIENGESELLSCHAFT (DE) 2002-03-20 EP disclosed
WO-2001000600-A1 N-SUBSTITUTED PERHYDRO DIAZINE BASF AKTIENGESELLSCHAFT (DE) 2001-01-04 WO disclosed