Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115577 | 0.86 | OPRM1 (0.41) | P2RY6OPRD1OPRK1OPRM1HSD17B10 | |
| SCHEMBL8533725 | 0.80 | P2RY6 (0.40) | P2RY6OPRD1OPRK1OPRM1HSD17B10 | |
| SCHEMBL9429585 | 0.77 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFMAOB | |
| SCHEMBL1743117 | 0.76 | HSD17B10 (0.43) | P2RY6OPRD1HSD17B10GRIN1GRIN2A | |
| SCHEMBL29402282 | 0.76 | HSD17B10 (0.43) | P2RY6OPRD1HSD17B10GRIN1GRIN2A | |
| SCHEMBL141450 | 0.74 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFMAOB | |
| SCHEMBL6550277 | 0.74 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFMAOB | |
| SCHEMBL6757638 | 0.74 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFMAOB | |
| SCHEMBL12847616 | 0.73 | HSD17B10 (0.38) | P2RY6OPRD1HSD17B10MAOBTP53 | |
| SCHEMBL5968018 | 0.72 | P2RY6 (0.40) | P2RY6OPRD1OPRK1OPRM1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219307-B1 | Stable radioiodine conjugates and methods for their synthesis | IMMUNOMEDICS INC (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-1024838-B1 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | IMMUNOMEDICS INC (US) | 2002-07-10 | — | — | EP | disclosed |
| EP-1219307-A2 | Stable radioiodine conjugates and methods for their synthesis | Immunomedics Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1024838-A1 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | Immunomedics, Inc. (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-0915710-A2 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | Immunomedics, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999011294-A1 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | IMMUNOMEDICS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1998008548-A2 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | IMMUNOMEDICS, INC. (US) | 1998-03-05 | — | — | WO | disclosed |