Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205496 | 0.80 | P2RY6 (0.53) | P2RY6HSD17B10KCNH2TP53CYP1A2 | |
| SCHEMBL5968018 | 0.80 | P2RY6 (0.40) | P2RY6GRIN1GRIN2AGRIN2BOPRD1 | |
| SCHEMBL7560309 | 0.80 | P2RY6 (0.40) | P2RY6GRIN1GRIN2AGRIN2BSLC7A5 | |
| SCHEMBL141450 | 0.75 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFTP53 | |
| SCHEMBL6550277 | 0.75 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFTP53 | |
| SCHEMBL6757638 | 0.75 | HSD17B10 (0.39) | P2RY6OPRD1HSD17B10MIFTP53 | |
| SCHEMBL7115577 | 0.74 | OPRM1 (0.41) | P2RY6GRIN1GRIN2AGRIN2BOPRD1 | |
| SCHEMBL1743117 | 0.74 | HSD17B10 (0.43) | P2RY6GRIN1GRIN2AGRIN2BOPRD1 | |
| SCHEMBL29402282 | 0.74 | HSD17B10 (0.43) | P2RY6GRIN1GRIN2AGRIN2BOPRD1 | |
| SCHEMBL12847616 | 0.73 | HSD17B10 (0.38) | P2RY6OPRD1HSD17B10TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915710-A2 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | Immunomedics, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998008548-A2 | STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS | IMMUNOMEDICS, INC. (US) | 1998-03-05 | — | — | WO | disclosed |