Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 6/20 | 0.45 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004219 | 1.00 | THRB (0.57) | THRBPPARAPPARDALDH1A1MAPT | |
| SCHEMBL13904873 | 0.94 | THRB (0.49) | THRBPPARAPPARDALDH1A1MAPT | |
| SCHEMBL10898936 | 0.92 | THRB (0.48) | THRBPPARAPPARDALDH1A1MAPT | |
| SCHEMBL10898934 | 0.92 | THRB (0.48) | THRBPPARAPPARDALDH1A1MAPT | |
| SCHEMBL12348073 | 0.92 | THRB (0.67) | THRBALDH1A1MAPTMMP2MMP3 | |
| SCHEMBL13655364 | 0.90 | THRB (0.69) | THRBPPARAPPARDALDH1A1TP53 | |
| SCHEMBL12348079 | 0.88 | THRB (0.61) | THRBALDH1A1MAPTMMP2MMP3 | |
| SCHEMBL471107 | 0.88 | THRB (0.61) | THRBALDH1A1MAPTMMP2MMP3 | |
| SCHEMBL2241855 | 0.85 | THRB (0.56) | THRBALDH1A1MAPTMMP2MMP3 | |
| SCHEMBL25123497 | 0.84 | THRB (0.57) | THRBALDH1A1MAPTMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622789-B1 | Sheet-like structures containing side chain polymers | BAYER AG (DE) | 2002-08-07 | — | — | EP | disclosed |
| US-5543267-A | Photo-induced optically anisotropic amorphous film materials from side group polymers | AGFA-GEVAERT AG (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0622789-A1 | Sheet-like structures containing side chain polymers | Agfa-Gevaert AG (DE) | 1994-11-02 | — | — | EP | disclosed |