SCHEMBL471107

SCHEMBL471107

C=CC(=O)OCCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.61
MMP2 P08253 8/20 0.58
MMP3 P08254 6/20 0.55
MMP1 P03956 1/20 0.55
MMP9 P14780 1/20 0.55
MMP13 P45452 1/20 0.55
MAPT P10636 2/20 0.52
ALDH1A1 P00352 1/20 0.52
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HRH3 Q9Y5N1 5/20 0.46
HRH2 P25021 4/20 0.46
HRH1 P35367 4/20 0.46
ABCB1 P08183 1/20 0.44
HPGD P15428 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25123497 0.96 THRB (0.57) THRBMMP2MMP3MMP1MMP9
SCHEMBL9880801 0.96 THRB (0.57) THRBMMP2MMP3MMP1MMP9
SCHEMBL7587630 0.96 THRB (0.57) THRBMMP2MMP3MMP1MMP9
SCHEMBL12348073 0.96 THRB (0.67) THRBMMP2MMP3MMP1MMP9
SCHEMBL12154697 0.94 THRB (0.55) THRBMMP2MMP3MMP1MMP9
SCHEMBL4331061 0.93 MMP2 (0.57) THRBMMP2MMP3MMP1MMP9
SCHEMBL5961806 0.93 MMP3 (0.58) THRBMMP2MMP3MMP1MMP9
SCHEMBL12646353 0.92 THRB (0.53) THRBMMP2MMP3MMP1MMP9
SCHEMBL8939360 0.92 HDAC1 (0.59) THRBMMP2MMP3MMP1MMP9
SCHEMBL7590582 0.92 HDAC1 (0.59) THRBMMP2MMP3MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-11926778-B2 Cholesteric liquid crystal based solid shell and production method thereof UNIVERSITÉ DU LUXEMBOURG (LU) 2024-03-12 US disclosed
CN-111989317-B Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, and polarizing plate 日本瑞翁株式会社 2023-12-01 CN disclosed
WO-2023189787-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023189966-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
CN-110382471-B Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound 日本瑞翁株式会社 2023-09-01 CN disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
CN-110099896-B Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound 日本瑞翁株式会社 2023-07-14 CN disclosed
WO-2023127401-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING PATTERNED CURED FILM 東京応化工業株式会社 2023-07-06 WO disclosed
US-20090209741-A1 POLYFUNCTIONAL COMPOUND, OPTICAL RECORDING MATERIAL, OPTICAL RECORDING MEDIUM, OPTICAL RECORDING/REPRODUCING APPARATUS, OPTICAL WAVEGUIDE MATERIAL, AND PHOTO-ALIGNMENT FILM MATERIAL NITTO DENKO CORPORATION (JP) 2009-08-20 US disclosed
US-20090182107-A1 METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND NITTO DENKO CORPORATION (JP) 2009-07-16 US disclosed
US-20090182107-A1 METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND NITTO DENKO CORPORATION (JP) 2009-07-16 US disclosed
EP-0955348-B1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME ASAHI GLASS CO LTD (JP) 2002-10-23 EP disclosed
EP-0622789-B1 Sheet-like structures containing side chain polymers BAYER AG (DE) 2002-08-07 EP disclosed
US-6180028-B1 ACRYLATED ESTERS ASAHI GLASS COMPANY LTD. (JP) 2001-01-30 US disclosed
EP-0955348-A1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME Asahi Glass Company Ltd. (JP) 1999-11-10 EP disclosed
US-5543267-A Photo-induced optically anisotropic amorphous film materials from side group polymers AGFA-GEVAERT AG (DE) 1996-08-06 US disclosed
US-5498363-A Electrorheological fluid AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-03-12 US disclosed
EP-0622789-A1 Sheet-like structures containing side chain polymers Agfa-Gevaert AG (DE) 1994-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209741-A1 POLYFUNCTIONAL COMPOUND, OPTICAL RECORDING MATERIAL, OPTICAL RECORDING MEDIUM, OPTICAL RECORDING/REPRODUCING APPARATUS, OPTICAL WAVEGUIDE MATERIAL, AND PHOTO-ALIGNMENT FILM MATERIAL CRY1, HAX1, F12 THRB 4619/4885MMP2 3478/4885MMP3 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.