Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037791 | 0.83 | ATM (0.47) | ALDH1A1PLGPLAUPLATTP53 | |
| SCHEMBL16753741 | 0.82 | PLG (0.41) | CYP3A4PLGPLAUPLATATM | |
| SCHEMBL657468 | 0.81 | ALDH1A1 (0.39) | CYP3A4ALDH1A1PLGPLAUPLAT | |
| SCHEMBL3981309 | 0.81 | HSD17B10 (0.48) | CYP3A4ALDH1A1MAOBPLGPLAU | |
| SCHEMBL3087598 | 0.80 | PLAU (0.59) | MAOBPLGPLAUPLAT | |
| SCHEMBL14323099 | 0.79 | PPARG (0.50) | CYP3A4ALDH1A1MAOBTP53CPN1 | |
| SCHEMBL9455644 | 0.78 | SRC (0.46) | ALDH1A1MAOBPLGPLAUPLAT | |
| SCHEMBL6215677 | 0.78 | TSHR (0.47) | PLGPLAUPLATTSHR | |
| SCHEMBL5002483 | 0.78 | CYP1A2 (0.54) | CYP3A4ALDH1A1MAOBTP53CPN1 | |
| SCHEMBL17128638 | 0.78 | ACHE (0.53) | MAOBPLGPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937063-B1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC SA (FR) | 2002-04-10 | — | — | EP | disclosed |