Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.50 |
| ▸ | RXRB | P28702 | 12/20 | 0.50 |
| ▸ | RARB | P10826 | 8/20 | 0.50 |
| ▸ | RXRG | P48443 | 8/20 | 0.50 |
| ▸ | RARG | P13631 | 7/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.47 |
| ▸ | RARA | P10276 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914352 | 0.82 | RXRA (0.54) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL15617210 | 0.80 | RXRA (0.56) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL4370337 | 0.77 | RARB (0.43) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL9006914 | 0.77 | RARB (0.35) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL6528854 | 0.77 | RXRA (0.53) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL20277839 | 0.77 | RXRA (0.53) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL2223568 | 0.73 | RARB (0.53) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL7759680 | 0.73 | RXRA (0.69) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL9521075 | 0.73 | RARB (0.60) | RXRARXRBRARBRXRGRARG | |
| SCHEMBL7559396 | 0.70 | RXRA (0.47) | RXRARXRBRARBRXRGRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | disclosed |
| EP-0986537-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development, S.N.C. (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1999050239-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-10-07 | — | — | WO | disclosed |