Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.60 |
| ▸ | RARG | P13631 | 12/20 | 0.60 |
| ▸ | RARA | P10276 | 6/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 8/20 | 0.42 |
| ▸ | RXRB | P28702 | 8/20 | 0.42 |
| ▸ | RXRG | P48443 | 7/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484589 | 0.81 | RARB (0.65) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL17914352 | 0.81 | RXRA (0.54) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9483828 | 0.80 | RARB (0.63) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL10899364 | 0.80 | RARB (0.63) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8901695 | 0.78 | RARB (0.59) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9483603 | 0.76 | RARB (0.58) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484092 | 0.76 | RARB (0.62) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484730 | 0.76 | RARB (0.62) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL14257543 | 0.76 | RARB (0.58) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9279402 | 0.75 | RARB (0.61) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412387-B1 | Diarylacetylenes, their process and use | BASF AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| US-5087637-A | Skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0412387-A2 | Diarylacetylenes, their process and use | BASF Aktiengesellschaft (DE) | 1991-02-13 | — | — | EP | disclosed |