Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622538 | 0.86 | TDP1 (0.43) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL9062505 | 0.80 | TDP1 (0.45) | TDP1HCAR2ALOX5APPESR1 | |
| SCHEMBL5533332 | 0.80 | TRPA1 (0.59) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL5907642 | 0.78 | TDP1 (0.56) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL114173 | 0.76 | TDP1 (0.58) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL6050179 | 0.75 | TDP1 (0.56) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL11670330 | 0.75 | TDP1 (0.56) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL7560563 | 0.74 | HCAR2 (0.46) | HCAR2LPAR1ALDH1A1TP53HPGD | |
| SCHEMBL28505436 | 0.73 | TDP1 (0.58) | TDP1HCAR2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL18656681 | 0.73 | HCAR2 (0.53) | TDP1HCAR2ALOX5AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |