Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560566 | 0.90 | HCAR2 (0.41) | HCAR2MAPTKDM4EPOLBLPAR1 | |
| SCHEMBL9582353 | 0.88 | HCAR2 (0.51) | HCAR2MAPTKDM4ELPAR1MAPK1 | |
| SCHEMBL9582347 | 0.84 | HCAR2 (0.47) | HCAR2MAPTKDM4ELPAR1TSHR | |
| SCHEMBL9062501 | 0.81 | HCAR2 (0.40) | HCAR2MAPTKDM4EPOLBLPAR1 | |
| SCHEMBL872826 | 0.77 | HCAR2 (0.53) | HCAR2MAPTKDM4ELPAR1TSHR | |
| SCHEMBL30688108 | 0.76 | LTB4R (0.54) | HCAR2MAPTKDM4EPOLBLPAR1 | |
| SCHEMBL7560570 | 0.74 | TDP1 (0.46) | HCAR2LPAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL11461421 | 0.73 | HCAR2 (0.56) | HCAR2MAPTKDM4ELPAR1TSHR | |
| SCHEMBL3883004 | 0.73 | HCAR2 (0.56) | HCAR2MAPTKDM4ELPAR1TSHR | |
| SCHEMBL16673205 | 0.73 | HCAR2 (0.49) | HCAR2MAPTKDM4EPOLBLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |