SCHEMBL7560604

SCHEMBL7560604

OC1CNCCC1c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 9/20 0.52
SLC6A4 P31645 9/20 0.52
SLC6A3 Q01959 8/20 0.52
KCNH2 Q12809 4/20 0.52
CYP2D6 P10635 2/20 0.52
KDM1A O60341 1/20 0.52
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
TLR9 Q9NR96 2/20 0.46
TLR8 Q9NR97 2/20 0.46
TLR7 Q9NYK1 2/20 0.46
REN P00797 5/20 0.46
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565322 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
SCHEMBL8870050 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
SCHEMBL407883 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
SCHEMBL11565325 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
SCHEMBL8471748 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
SCHEMBL8317532 0.80 KDM1A (0.50) SLC6A2SLC6A4KDM1AMAOAMAOB
Hydrochloric Acid SCHEMBL11555721 0.78 SLC18A3 (0.49) KDM1AMAOAMAOB
Hydrochloric Acid SCHEMBL442396 0.78 SLC18A3 (0.49) KDM1AMAOAMAOB
Hydrochloric Acid SCHEMBL11555730 0.78 SLC18A3 (0.49) KDM1AMAOAMAOB
SCHEMBL3867096 0.77 HTR2C (0.46) SLC6A2SLC6A4SLC6A3KDM1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002076440-A2 METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES ELAN PHARMACEUTICALS, INC. (US) 2002-10-03 WO disclosed