Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.42 |
| ▸ | ADH1A | P07327 | 4/20 | 0.42 |
| ▸ | ADH1C | P00326 | 3/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247547 | 0.89 | ADH1B (0.52) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19872335 | 0.82 | ADH1B (0.56) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL4110326 | 0.79 | ADH1B (0.43) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL28267502 | 0.78 | ADH1B (0.60) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL27800195 | 0.77 | ADH1B (0.61) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL13207250 | 0.76 | EPHX2 (0.43) | LMNA | |
| SCHEMBL2550326 | 0.76 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL4720502 | 0.74 | L3MBTL3 (0.42) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL2862492 | 0.74 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL2553841 | 0.74 | HRH3 (0.44) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017399-A4 | CAMPTOTHECIN ANALOGS AND METHODS OF PREPARATION THEREOF | UNIV PITTSBURGH (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1017399-A1 | CAMPTOTHECIN ANALOGS AND METHODS OF PREPARATION THEREOF | University of Pittsburgh (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999009996-A1 | CAMPTOTHECIN ANALOGS AND METHODS OF PREPARATION THEREOF | UNIVERSITY OF PITTSBURGH (US) | 1999-03-04 | — | — | WO | disclosed |