Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558043 | 0.79 | ROCK2 (0.43) | CHRNB2CHRNA4KMT2AACP1EPHX2 | |
| SCHEMBL7567956 | 0.77 | KMT2A (0.43) | KMT2AACP1EPHX2ROCK2 | |
| SCHEMBL7567797 | 0.72 | MME (0.51) | CHRNB2CHRNA4KMT2AACP1EPHX2 | |
| SCHEMBL7567808 | 0.71 | KMT2A (0.60) | CHRNB2CHRNA4KMT2AACP1EPHX2 | |
| SCHEMBL6508976 | 0.71 | KMT2A (0.67) | CHRNB2CHRNA4KMT2AACP1EPHX2 | |
| SCHEMBL7598334 | 0.69 | KMT2A (0.46) | CHRNB2CHRNA4KMT2AACP1EPHX2 | |
| SCHEMBL29262813 | 0.68 | EPHX2 (0.57) | KMT2AEPHX2 | |
| SCHEMBL31227621 | 0.67 | KMT2A (0.60) | NCOA1NCOA3CHRNB2CHRNA4KMT2A | |
| SCHEMBL29262812 | 0.67 | EPHX2 (0.59) | EPHX2 | |
| SCHEMBL27586873 | 0.66 | ROCK2 (0.50) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |