Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CPN1 | P15169 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567808 | 0.77 | KMT2A (0.60) | KLK7KMT2AACP1EPHX2CHRNB2 | |
| SCHEMBL7567956 | 0.77 | KMT2A (0.43) | KMT2AACP1EPHX2 | |
| SCHEMBL7558043 | 0.77 | ROCK2 (0.43) | KMT2AACP1JAK3EPHX2CHRNB2 | |
| SCHEMBL7598334 | 0.77 | KMT2A (0.46) | KLK7KMT2AACP1EPHX2CHRNB2 | |
| SCHEMBL6508976 | 0.76 | KMT2A (0.67) | KLK7KMT2AACP1JAK3EPHX2 | |
| SCHEMBL6050177 | 0.76 | CPN1 (0.62) | KMT2ACPN1CPB2CHRNB2CHRNB4 | |
| SCHEMBL26503529 | 0.72 | METAP2 (0.55) | KLK7KMT2AEPHX2 | |
| SCHEMBL7494113 | 0.71 | KLK7 (0.40) | KLK7JAK3 | |
| SCHEMBL7563657 | 0.71 | KLK7 (0.40) | KLK7JAK3 | |
| SCHEMBL6508972 | 0.70 | KMT2A (0.51) | KMT2AACP1CPN1CPB2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187810-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000071518-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2000-11-30 | — | — | WO | disclosed |