⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094544 | 0.83 | TKT (0.55) | — | |
| SCHEMBL2493947 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL23059363 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL5691391 | 0.79 | — | — | |
| SCHEMBL479344 | 0.78 | LMNA (0.61) | — | |
| SCHEMBL23094501 | 0.78 | LMNA (0.50) | — | |
| SCHEMBL12877484 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL1317193 | 0.77 | DHFR (0.64) | — | |
| SCHEMBL3477329 | 0.77 | — | — | |
| SCHEMBL11388077 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122006472-A | Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method | 沃顿科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-115924846-A | Membrane separation method for recovering purge gas from organic alcohol synthesis | 宁波巨化化工科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | claimed |
| EP-0051879-B1 | SUBSTITUTED PYRIMIDINES, THEIR SYNTHESIS AND COMPOSITIONS CONTAINING THEM, THEIR USE IN MEDICINE AND INTERMEDIATES FOR MAKING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-05 | — | — | EP | claimed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | claimed |
| JP-6009576-A | — | — | None | — | — | JP | disclosed |
| WO-2026097624-A1 | METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH | 沃顿科技股份有限公司 | 2026-05-15 | — | — | WO | disclosed |
| CN-122006472-A | Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method | 沃顿科技股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | WASHINGTON UNIVERISTY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230322667-A1 | DIHYDROFOLATE SYNTHASE (DHFS) INHIBITING AGENTS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-4568744-A | ANTIBACTERICIDES AND DIRUETIC INTERMEDIATES | BURROUGHS WELLCOME CO. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4438267-A | ANTIBACTERIAL AGENTS | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 1984-03-20 | — | — | US | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |
| EP-0051879-A2 | Substituted pyrimidines, their synthesis and compositions containing them, their use in medicine and intermediates for making them | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-19 | — | — | EP | disclosed |
| US-4255574-A | REACTING B-ALKOXY-PROPIONITRILE WITH AN ALKALI METAL ALCOHOLATE AND CONDENSING THE REACTION PRODUCT WITH GUANIDINE | HOFFMANN-LA ROCHE INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4143227-A | FROM THE 2,4-DIAMINO-5-OXY OR HALOMETHYL-PYRIMIDINE AND A 1,2-DIALKOXY OR METHYLENEDIOXY-BENZENE IN AN ACID | HOFFMANN-LA ROCHE INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4116958-A | ORGANIC SYNTHETIC METHODS BENZYLPYRIMIDINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4116958-A | ORGANIC SYNTHETIC METHODS BENZYLPYRIMIDINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1978-09-26 | — | — | US | disclosed |