⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143450 | 0.76 | — | — | |
| SCHEMBL10979619 | 0.76 | — | — | |
| SCHEMBL2813908 | 0.76 | NPC1 (0.38) | — | |
| SCHEMBL1655684 | 0.74 | ALOX5 (0.39) | — | |
| Bromide SCHEMBL12482879 | 0.74 | NPC1 (0.37) | — | |
| SCHEMBL30523 | 0.72 | TRIM24 (0.45) | — | |
| SCHEMBL7675118 | 0.72 | NPC1 (0.39) | — | |
| SCHEMBL30522 | 0.71 | NPC1 (0.38) | — | |
| SCHEMBL83810 | 0.71 | KDM4E (0.41) | — | |
| SCHEMBL7037632 | 0.70 | EGLN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107406-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | US | claimed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |