SCHEMBL1655684

SCHEMBL1655684

C=CCc1cccn1CC=C

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
NPC1 O15118 9/20 0.37
KMT2A Q03164 8/20 0.37
RAB9A P51151 8/20 0.36
MEN1 O00255 5/20 0.36
ALDH1A1 P00352 4/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7675118 0.82 NPC1 (0.39) ALOX5NPC1KMT2ARAB9AMEN1
SCHEMBL17505975 0.77 ALDH1A1 (0.33) NPC1RAB9AALDH1A1MAPTHTT
SCHEMBL10984099 0.77 KMT2A (0.37) ALOX5NPC1KMT2ARAB9AMEN1
SCHEMBL7963893 0.76 PTGS1 (0.43) ALOX5NPC1KMT2ARAB9AMEN1
SCHEMBL11241235 0.74 NPC1 (0.41) ALOX5NPC1KMT2ARAB9AMEN1
SCHEMBL3720066 0.74 GAA (0.38) ALOX5NPC1KMT2ARAB9AMEN1
SCHEMBL7560764 0.74
SCHEMBL10979619 0.72
SCHEMBL9635921 0.72
SCHEMBL2813908 0.72 NPC1 (0.38) ALOX5NPC1KMT2ARAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271225-B1 INDENE DERIVATIVES AND METHODS H. LUNDBECK A/S (DK) 1993-10-13 EP claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
CN-108026200-B Process for selective oligomerization of ethylene 韩泽圭 2020-10-16 CN disclosed
US-10399912-B2 Selective oligomerization reaction process of ethylene HAN TAEK KYU (KR) 2019-09-03 US disclosed
US-20180237360-A1 SELECTIVE OLIGOMERIZATION REACTION PROCESS OF ETHYLENE HAN TAEK KYU (KR) 2018-08-23 US disclosed
EP-3345935-A1 SELECTIVE OLIGOMERIZATION REACTION PROCESS OF ETHYLENE Han, Taek Kyu (KR) 2018-07-11 EP disclosed
WO-2014069989-A1 PROCESS FOR PRODUCING AN OLIGO(ALPHA-OLEFIN) AND THE USE OF A PARTICULAR FORM OF METHYLALUMINOXANE IN SUCH PROCESS STICHTING DUTCH POLYMER INSTITUTE (NL) 2014-05-08 WO disclosed
US-7927486-B2 Polymer modified porous substrate for solid phase extraction AGILENT TECHNOLOGIES, INC (US) 2011-04-19 US disclosed
EP-1899050-A2 POLAR FUNCTIONIZED POLYMER MODIFIED POROUS SUBSTRATE FOR SOLID PHASE EXTRACTION Varian, Inc. (US) 2008-03-19 EP disclosed
US-20080035558-A1 Polymer modified porous substrate for solid phase extraction AGILENT TECHNOLOGIES, INC. 2008-02-14 US disclosed
US-7311825-B2 Polymer modified porous substrate for solid phase extraction VARIAN, INC. (US) 2007-12-25 US disclosed
US-20060247362-A1 Polymer modified porous substrate for solid phase extraction VARIAN, INC. 2006-11-02 US disclosed
US-20060247361-A1 Polar functionalized polymer modified porous substrate for solid phase extraction VARIAN, INC. 2006-11-02 US disclosed
EP-0778835-A4 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS UNIV VIRGINIA (US) 1999-02-03 EP disclosed
EP-0778835-A1 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS UNIVERSITY OF VIRGINIA (US) 1997-06-18 EP disclosed
WO-1996006093-A1 7-AZABICYCLO[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS UNIVERSITY OF VIRGINIA (US) 1996-02-29 WO disclosed
EP-0217081-A1 Process for applying a layer of an electrically conductive material to another electrically conductive material BASF Aktiengesellschaft (DE) 1987-04-08 EP disclosed
US-4647576-A Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis WARNER-LAMBERT COMPANY (US) 1987-03-03 US disclosed
EP-0179559-A2 Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis WARNER-LAMBERT COMPANY (US) 1986-04-30 EP disclosed
US-4083851-A HYDROGENATION, CATALYST ON SUPPORT DIAMOND SHAMROCK CORPORATION (US) 1978-04-11 US disclosed