Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.48 |
| ▸ | RXRB | P28702 | 14/20 | 0.48 |
| ▸ | RXRG | P48443 | 14/20 | 0.48 |
| ▸ | RARG | P13631 | 7/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476890 | 1.00 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7560513 | 0.88 | RXRA (0.40) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7560510 | 0.88 | RXRA (0.40) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6478019 | 0.85 | RXRA (0.39) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7563931 | 0.85 | RXRA (0.39) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6473737 | 0.83 | RXRA (0.42) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7558397 | 0.83 | RXRA (0.42) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6526066 | 0.80 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6472528 | 0.80 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7559742 | 0.80 | RXRA (0.56) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | disclosed |
| EP-0986537-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development, S.N.C. (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1999050239-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-10-07 | — | — | WO | disclosed |