Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.42 |
| ▸ | RXRB | P28702 | 12/20 | 0.42 |
| ▸ | RXRG | P48443 | 12/20 | 0.42 |
| ▸ | RARG | P13631 | 7/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473737 | 1.00 | RXRA (0.42) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7560853 | 0.83 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6476890 | 0.83 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7560392 | 0.77 | PLA2G4A (0.36) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7560394 | 0.77 | PLA2G4A (0.36) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7558312 | 0.74 | RXRA (0.41) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL2910172 | 0.73 | RARB (0.61) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7563931 | 0.72 | RXRA (0.39) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6478019 | 0.72 | RXRA (0.39) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6473558 | 0.72 | MRGPRX4 (0.35) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |
| US-6444709-B1 | SKIN DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; CARDIOVASCULAR DISORDERS | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2002-09-03 | — | — | US | disclosed |