Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532807 | 0.83 | LMNA (0.35) | LMNA | |
| SCHEMBL1005858 | 0.82 | OPRM1 (0.44) | LMNA | |
| SCHEMBL9626011 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL4458439 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL5686549 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL5684301 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL9212678 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL5686908 | 0.80 | ACE2 (0.45) | LMNA | |
| SCHEMBL8842826 | 0.80 | LMNA (0.35) | LMNA | |
| SCHEMBL5684181 | 0.80 | ACE2 (0.45) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068434-A1 | NOVEL DIPHOSPHINES AND A METHOD FOR THEIR PRODUCTION | CELANESE CHEMICALS EUROPE GMBH (DE) | 2002-09-06 | — | — | WO | disclosed |
| EP-0009683-B1 | BASIC PHENYL ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION OF THESE ETHERS AND COMPOSITIONS | MERCK PATENT GmbH (DE) | 1983-08-10 | — | — | EP | disclosed |