Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765522 | 0.89 | BDKRB1 (0.50) | BDKRB1METCARM1PRMT6METAP2 | |
| Hydrochloric Acid SCHEMBL2546804 | 0.88 | BDKRB1 (0.49) | BDKRB1METCARM1PRMT6METAP2 | |
| SCHEMBL754425 | 0.86 | PPARD (0.44) | BDKRB1CARM1PRMT6TRPV1FAAH | |
| SCHEMBL764468 | 0.85 | BDKRB1 (0.48) | BDKRB1METCARM1PRMT6SLC6A2 | |
| SCHEMBL10121264 | 0.84 | BDKRB1 (0.49) | BDKRB1METAP2PPARDPTGER4CNR1 | |
| SCHEMBL765524 | 0.84 | BDKRB1 (0.51) | BDKRB1METPTGER4CNR1 | |
| SCHEMBL765808 | 0.79 | BDKRB1 (0.48) | BDKRB1METCARM1PRMT6METAP2 | |
| SCHEMBL757026 | 0.79 | BDKRB1 (0.45) | BDKRB1PTGER4CNR1 | |
| SCHEMBL10121221 | 0.79 | BDKRB1 (0.47) | BDKRB1METPTGER4SLC6A4KCNH2 | |
| SCHEMBL12239074 | 0.78 | BDKRB1 (0.49) | BDKRB1METCARM1PRMT6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |