Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 12/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765535 | 0.91 | BDKRB1 (0.57) | BDKRB1PTGER4PTGER2CNR1FPR2 | |
| SCHEMBL754249 | 0.82 | BDKRB1 (0.52) | BDKRB1CNR1 | |
| SCHEMBL10121364 | 0.81 | BDKRB1 (0.58) | BDKRB1PTGER4PTGER2CNR1 | |
| SCHEMBL756132 | 0.79 | BDKRB1 (0.39) | BDKRB1PTGER4CNR1 | |
| SCHEMBL3726665 | 0.77 | BDKRB1 (0.48) | BDKRB1CNR1 | |
| SCHEMBL14856694 | 0.76 | BDKRB1 (0.48) | BDKRB1CNR1 | |
| SCHEMBL754425 | 0.75 | PPARD (0.44) | BDKRB1 | |
| SCHEMBL10121536 | 0.74 | BDKRB1 (0.60) | BDKRB1PTGER4CNR1 | |
| SCHEMBL3722571 | 0.74 | CACNA1I (0.36) | BDKRB1CNR1 | |
| SCHEMBL765524 | 0.74 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2CNR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |
| EP-2188254-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009027450-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |