Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547691 | 0.90 | BDKRB1 (0.53) | PPARDBDKRB1ROCK2CHRM4 | |
| SCHEMBL756132 | 0.86 | BDKRB1 (0.39) | PPARDBDKRB1FAAHTRPV1CARM1 | |
| SCHEMBL12262806 | 0.85 | BDKRB1 (0.55) | PPARDBDKRB1L3MBTL1ALDH1A1 | |
| SCHEMBL755280 | 0.85 | BDKRB1 (0.43) | BDKRB1FAAHTRPV1CHRM4 | |
| SCHEMBL12239072 | 0.83 | BDKRB1 (0.51) | PPARDBDKRB1CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL14856425 | 0.82 | BDKRB1 (0.48) | BDKRB1ROCK2FAAHTRPV1L3MBTL1 | |
| SCHEMBL2788425 | 0.81 | EPHX2 (0.41) | BDKRB1FAAHTRPV1L3MBTL1ALDH1A1 | |
| SCHEMBL10121264 | 0.81 | BDKRB1 (0.49) | PPARDBDKRB1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL765537 | 0.81 | BDKRB1 (0.54) | PPARDBDKRB1CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL765652 | 0.81 | BDKRB1 (0.49) | PPARDBDKRB1CARM1PRMT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |