Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578122 | 0.95 | TSHR (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4623822 | 0.91 | TSHR (0.66) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28671372 | 0.91 | TSHR (0.66) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28311362 | 0.88 | TSHR (0.71) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL23668736 | 0.86 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9329297 | 0.86 | TSHR (0.69) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11868077 | 0.86 | TSHR (0.69) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Acrylic Acid SCHEMBL20787954 | 0.85 | THRB (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL27438198 | 0.85 | TSHR (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11033659 | 0.84 | TSHR (0.71) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068527-A2 | NOVEL β-OXO COMPOUNDS AND THEIR USE IN PHOTORESIST | ARCH SPECIALTY CHEMICALS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |