Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL26090179 | 0.92 | TSHR (0.52) | TSHRMEN1THRBHTTKMT2A | |
| Acrylic Acid SCHEMBL29726247 | 0.87 | ALOX15 (0.52) | TSHRALOX15HSD17B10MEN1THRB | |
| Acrylic Acid SCHEMBL2126766 | 0.87 | ALOX15 (0.52) | TSHRALOX15HSD17B10MEN1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL27600939 | 0.85 | THRB (0.53) | TSHRALOX15HSD17B10MEN1THRB | |
| Acrylic Acid SCHEMBL9243919 | 0.85 | ALOX15 (0.50) | TSHRALOX15HSD17B10MEN1THRB | |
| SCHEMBL6536784 | 0.84 | MEN1 (0.44) | TSHRMEN1THRBHTTKMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL9306495 | 0.83 | TSHR (0.65) | TSHRMEN1THRBHTTKMT2A | |
| Acrylic Acid SCHEMBL6067722 | 0.83 | ALOX15 (0.48) | TSHRALOX15HSD17B10MEN1THRB | |
| Triethylene Glycol SCHEMBL2819414 | 0.82 | TSHR (0.63) | TSHRHSD17B10MEN1THRBHTT | |
| Acrylic Acid SCHEMBL6067680 | 0.82 | ALOX15 (0.47) | TSHRALOX15HSD17B10MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068527-A2 | NOVEL β-OXO COMPOUNDS AND THEIR USE IN PHOTORESIST | ARCH SPECIALTY CHEMICALS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |