Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25552740 | 0.88 | ALDH1A1 (0.50) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL421286 | 0.87 | SYK (0.61) | SYKALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL30544325 | 0.87 | SYK (0.57) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL25908037 | 0.86 | ALDH1A1 (0.53) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL6932926 | 0.86 | ALDH1A1 (0.53) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL19295062 | 0.86 | PRSS1 (0.44) | SYKALDH1A1MAPK1MAPTPRSS1 | |
| SCHEMBL12475781 | 0.86 | SYK (0.62) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL7907133 | 0.86 | SYK (0.62) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL6016839 | 0.86 | SYK (0.57) | SYKALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL22657971 | 0.86 | SYK (0.56) | SYKALDH1A1MAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060333-B2 | Aminocarbamoyl compounds for the treatment of viral infections | HOFFMANN-LA ROCHE INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-20230277677-A1 | POLYMERIC CONJUGATES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-09-07 | — | — | US | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| US-11666656-B2 | Polymeric conjugates and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-06-06 | — | — | US | disclosed |
| WO-2022043374-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | disclosed |
| WO-2017145164-A1 | POLYMERIC CONJUGATES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-08-31 | — | — | WO | disclosed |
| US-20120053165-A1 | Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators | PFIZER INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053165-A1 | Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators | BACE1, BACE2, PSEN1 | SYK 2765/4885ALDH1A1 1903/4885MAPK1 2988/4885 |
| US-11666656-B2 | Polymeric conjugates and uses thereof | CD44, DCLRE1A, CD74 | SYK 2854/4885ALDH1A1 2653/4885MAPK1 3732/4885 |
| US-20230277677-A1 | POLYMERIC CONJUGATES AND USES THEREOF | CD44, DCLRE1A, CD74 | SYK 2854/4885ALDH1A1 2653/4885MAPK1 3732/4885 |
| US-12060333-B2 | Aminocarbamoyl compounds for the treatment of viral infections | SARS1, BCAT1, SLC1A5 | SYK 4012/4885ALDH1A1 2749/4885MAPK1 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.