Sulisobenzone

Sulisobenzone

SCHEMBL7561904

COc1cc(O)c(C(=O)c2ccccc2)cc1S(=O)(=O)O.COc1ccc(C(=O)c2ccc(OC)cc2O)c(O)c1

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.82
LMNA P02545 7/20 0.82
ALDH1A1 P00352 4/20 0.82
KMT2A Q03164 2/20 0.82
HPGD P15428 5/20 0.68
HTT P42858 4/20 0.68
MAPK1 P28482 3/20 0.68
CYP1A2 P05177 2/20 0.68
PGR P06401 2/20 0.68
SLC6A2 P23975 2/20 0.68
CYP2C19 P33261 2/20 0.68
CYP2D6 P10635 1/20 0.68
PDE4A P27815 1/20 0.68
HRH1 P35367 1/20 0.68
SLC6A3 Q01959 1/20 0.68
PDE4D Q08499 1/20 0.68
CYP3A4 P08684 3/20 0.57
KDM4E B2RXH2 2/20 0.57
HSD17B10 Q99714 2/20 0.57
RECQL P46063 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulisobenzone SCHEMBL4743699 0.99 MAPT (0.84) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL2838157 0.97 MAPT (0.77) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL27762304 0.93 MAPT (0.71) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL8815769 0.92 LMNA (0.84) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL30433307 0.92 MAPT (0.66) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL414485 0.92 MAPT (0.66) MAPTLMNAALDH1A1KMT2AHPGD
Sulisobenzone SCHEMBL27479468 0.92 MAPT (0.72) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL6054787 0.91 MAPT (0.64) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL345162 0.91 MAPT (0.64) MAPTLMNAALDH1A1KMT2AHPGD
SCHEMBL29967586 0.91 MAPT (0.64) MAPTLMNAALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717079-B1 Injection molded article for photographic photosensitive material, molding method thereof and package using the same FUJI PHOTO FILM CO LTD (JP) 2002-07-24 EP disclosed