SCHEMBL345162

SCHEMBL345162

COc1ccc(C(=O)c2cc(S(=O)(=O)O)c(OC)cc2O)c(O)c1.[NaH]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.64
KMT2A Q03164 6/20 0.64
LMNA P02545 5/20 0.64
ALDH1A1 P00352 3/20 0.64
NPC1 O15118 5/20 0.63
RAB9A P51151 4/20 0.63
CYP3A4 P08684 5/20 0.56
HPGD P15428 4/20 0.56
CYP2C19 P33261 3/20 0.56
CYP1A2 P05177 2/20 0.56
PGR P06401 2/20 0.56
SLC6A2 P23975 2/20 0.56
ADORA3 P0DMS8 1/20 0.56
AR P10275 1/20 0.56
CHRM1 P11229 1/20 0.56
ALOX15 P16050 1/20 0.56
TBXA2R P21731 1/20 0.56
ADRA1A P35348 1/20 0.56
HIF1A Q16665 1/20 0.56
MAPK1 P28482 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054787 1.00 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL30433307 0.99 MAPT (0.66) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL414485 0.99 MAPT (0.66) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL10491558 0.97 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL29967586 0.97 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL29466728 0.97 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL31202078 0.97 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL10491875 0.97 MAPT (0.64) MAPTKMT2ALMNAALDH1A1NPC1
SCHEMBL9619909 0.92 NPC1 (0.63) MAPTKMT2ALMNAALDH1A1NPC1
Sulisobenzone SCHEMBL7561904 0.91 MAPT (0.82) MAPTKMT2ALMNAALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120237466-A1 PHOTO-FILTERING COMPOSITION FOR HAIR AND SCALP GRAHAM JAMES (US) 2012-09-20 US claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-6159918-A Transparent/translucent liquid enzyme compositions in clear bottles comprising UV absorber UNILEVER HOME & PERSONAL CARE U.S.A., DIVISION OF CONOPCO, INC. (US) 2000-12-12 US claimed
EP-0325267-B1 Peroxide gel dentifrice compositions CARTER WALLACE (US) 1994-05-11 EP claimed
US-4391894-A BASIC DYE REACTED WITH ORGANIC ACID DISSOLVED IN A PHOTOSENSITIVE DIAZO COMPOSITION POLYCHROME CORPORATION (US) 1983-07-05 US claimed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US claimed
EP-4692260-A1 KIT FOR THREE-COMPONENT COATING COMPOSITION, THREE-COMPONENT COATING COMPOSITION, AND IN-MOLD COATING METHOD Kansai Paint Co., Ltd (JP) 2026-02-11 EP disclosed
US-20260021615-A1 COATING COMPOSITION AND IN-MOLD COATING METHOD KANSAI PAINT CO LTD (JP) 2026-01-22 US disclosed
US-12485593-B2 Method for forming in-mold coating multi-layer coating film KANSAI PAINT CO., LTD. (JP) 2025-12-02 US disclosed
US-20250295566-A1 DIESTER HAIR STYLING FORMULATIONS, AND USES THEREOF Chembeau LLC 2025-09-25 US disclosed
US-20250248913-A1 HAIR TREATMENT FORMULATIONS AND USES THEREOF Chembeau LLC 2025-08-07 US disclosed
US-20250230338-A1 THERMOSETTING COATING MATERIAL COMPOSITION, COATED ARTICLE, AND IN-MOLD COATING METHOD KANSAI PAINT CO., LTD. (JP) 2025-07-17 US disclosed
US-12325805-B2 Coating composition and in-mold coating method KANSAI PAINT CO., LTD. (JP) 2025-06-10 US disclosed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4171974-A Aqueous alkali developable negative working lithographic printing plates POLYCHROME CORPORATION (US) 1979-10-23 US disclosed
US-4169005-A LAMINATING ADHESIVE, PLASTIC FILM, CURING THE TOP COAT CHAMPION INTERNATIONAL CORPORATION (US) 1979-09-25 US disclosed
US-4058462-A System for sustained release of phenolic material from porous granules of insoluble polymeric phenolic complexes GAF CORPORATION (US) 1977-11-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US disclosed
US-3931442-A Temporary modification of a pattern mask for use in forming a color CRT screen and a process for modifying the same GTE SYLVANIA INCORPORATED (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295566-A1 DIESTER HAIR STYLING FORMULATIONS, AND USES THEREOF SUCLG1, SMS, SRM MAPT 1660/4885KMT2A 1701/4885LMNA 2295/4885
US-20260021615-A1 COATING COMPOSITION AND IN-MOLD COATING METHOD VIM, VCL, C9 MAPT 688/4885KMT2A 390/4885LMNA 831/4885
US-20120237466-A1 PHOTO-FILTERING COMPOSITION FOR HAIR AND SCALP CUTA, PTMA, GYPA MAPT 2428/4885KMT2A 2718/4885LMNA 1895/4885
US-20250248913-A1 HAIR TREATMENT FORMULATIONS AND USES THEREOF FHIT, SUCLG1, TES MAPT 2315/4885KMT2A 613/4885LMNA 839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.