Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562027 | 1.00 | REN (0.41) | RENSSTR5ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL7562024 | 0.82 | REN (0.39) | RENSSTR5ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL6043888 | 0.81 | REN (0.49) | RENSSTR5ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL6043894 | 0.81 | REN (0.49) | RENSSTR5ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL7076705 | 0.76 | REN (0.46) | RENSSTR5ALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL6043325 | 0.75 | REN (0.71) | REN | |
| SCHEMBL6043333 | 0.75 | REN (0.71) | REN | |
| SCHEMBL6042526 | 0.73 | REN (0.47) | RENSSTR5ALDH1A1SMN1; SMN2ACKR3 | |
| SCHEMBL8183012 | 0.73 | REN (0.47) | RENSSTR5ALDH1A1SMN1; SMN2ACKR3 | |
| SCHEMBL6043793 | 0.69 | REN (0.56) | RENSSTR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |