Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560742 | 0.85 | CACNA1A (0.43) | MEN1KMT2AALDH1A1CACNA1ACACNA2D1 | |
| SCHEMBL8936886 | 0.84 | KMT2A (0.39) | MEN1KMT2AALDH1A1CACNA1ACACNA2D1 | |
| SCHEMBL7561509 | 0.84 | KMT2A (0.39) | MEN1KMT2AALDH1A1CACNA1ACACNA2D1 | |
| SCHEMBL7561512 | 0.84 | KMT2A (0.39) | MEN1KMT2AALDH1A1CACNA1ACACNA2D1 | |
| SCHEMBL7563154 | 0.77 | MAOB (0.46) | MEN1KMT2AALDH1A1MAOBMAOA | |
| SCHEMBL8589584 | 0.76 | KMT2A (0.34) | KMT2AALDH1A1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL7562281 | 0.75 | SIRT1 (0.40) | ALDH1A1LMNAMAOBMAOAGAA | |
| SCHEMBL8589559 | 0.75 | MAOB (0.39) | MEN1KMT2AALDH1A1LMNACACNA1A | |
| SCHEMBL7561784 | 0.75 | KMT2A (0.34) | KMT2AGHSR | |
| SCHEMBL8532155 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799215-B1 | PROCESS FOR PREPARING BENZYL-SUBSTITUTED RHODANINE DERIVATIVES | LILLY CO ELI (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-0799215-A4 | PROCESS FOR PREPARING BENZYL-SUBSTITUTED RHODANINE DERIVATIVES | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0799215-A1 | PROCESS FOR PREPARING BENZYL-SUBSTITUTED RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5563277-A | REDUCING THIAZOLIDINONE WITH TWO MOLES OF AN ALKALI OR ALKALI-EARTH METALS IN PRESENCE OF AMMONIA OR AMINE; ANTIINFLAMMATORY AGENT | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1996019466-A1 | PROCESS FOR PREPARING BENZYL-SUBSTITUTED RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |