Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.64 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.64 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.64 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.64 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL443839 | 0.99 | P2RY2 (0.63) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL3164897 | 0.91 | P2RY2 (0.65) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL8862998 | 0.91 | NT5E (0.59) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL9853314 | 0.91 | NT5E (0.59) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL8970175 | 0.91 | NT5E (0.59) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL6699115 | 0.90 | P2RY1 (0.57) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL7231385 | 0.90 | P2RY2 (0.64) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL5320373 | 0.89 | P2RY2 (0.63) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL2791974 | 0.89 | P2RY2 (0.63) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 | |
| SCHEMBL10824469 | 0.89 | P2RY1 (0.63) | P2RY2P2RY1SRCSMN1; SMN2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506352-A | Process for the synthesis of 9-(β-D-arabinofuranosyl)adenine, 5'-phosphate | WARNER-LAMBERT COMPANY (US) | 1996-04-09 | — | — | US | claimed |
| EP-1320540-B9 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMA (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1320540-B1 | PEPTIDOMIMETIC PROTEASE INHIBITORS | VERTEX PHARMA (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1061922-A1 | USE OF $i(N)-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0657465-B1 | Liponucleotide compounds | BORYUNG PHARM (KR) | 1999-09-01 | — | — | EP | disclosed |
| WO-1999040916-A1 | USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1999-08-19 | — | — | WO | disclosed |
| EP-0487719-B1 | PROCESS FOR THE PREPARATION OF 9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE 5'-PHOSPHATE | ASH STEVENS INC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0657465-A2 | Liponucleotide compounds | Boryung Pharmaceutical Co., Ltd. (KR) | 1995-06-14 | — | — | EP | disclosed |
| US-4357324-A | Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1982-11-02 | — | — | US | disclosed |
| US-4093714-A | VIRICIDES | ICN PHARMACEUTICALS, INC. (US) | 1978-06-06 | — | — | US | disclosed |