Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.56 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853314 | 1.00 | NT5E (0.59) | NT5EP2RY2P2RY1ADORA1SRC | |
| SCHEMBL8862998 | 1.00 | NT5E (0.59) | NT5EP2RY2P2RY1ADORA1SRC | |
| SCHEMBL756245 | 0.91 | P2RY2 (0.64) | P2RY2P2RY1ADORA1SRCSMN1; SMN2 | |
| Water SCHEMBL443839 | 0.90 | P2RY2 (0.63) | P2RY2P2RY1ADORA1SRCSMN1; SMN2 | |
| SCHEMBL8836780 | 0.89 | GK (0.57) | NT5EP2RY2P2RY1ADORA1SRC | |
| SCHEMBL8836084 | 0.85 | NT5E (0.60) | NT5EP2RY2P2RY1ADORA1SRC | |
| SCHEMBL8836065 | 0.85 | NT5E (0.60) | NT5EP2RY2P2RY1ADORA1SRC | |
| SCHEMBL27120145 | 0.83 | AHCY (0.58) | NT5EADORA1SMN1; SMN2AHCYADORA2A | |
| SCHEMBL3164897 | 0.83 | P2RY2 (0.65) | P2RY2P2RY1ADORA1SRCSMN1; SMN2 | |
| SCHEMBL9395428 | 0.82 | NT5E (0.57) | NT5EP2RY2P2RY1ADORA1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0671410-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | disclosed |
| US-5420115-A | Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides | BURROUGHS WELLCOME CO. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0417999-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |