Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246606 | 0.92 | TSHR (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL14208609 | 0.89 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL1888838 | 0.89 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL1887907 | 0.87 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL1884652 | 0.87 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL14208681 | 0.87 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL18031805 | 0.86 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15435748 | 0.85 | THRB (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL36589 | 0.84 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL246414 | 0.84 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963398-B1 | ORGANIC/INORGANIC COMPOSITES WITH LOW HYDROXYL GROUP CONTENT, METHOD FOR THEIR PRODUCTION AND APPLICATION | INST NEUE MAT GEMEIN GMBH (DE) | 2002-08-07 | — | — | EP | disclosed |
| US-6303730-B1 | NONHYDROLYTIC CONDENSATION OF CHLOROSILANES WITH POLYMERIZABLE GROUPS AND OPTIONALLY FLUORINATED GROUPS, WITH THE HELP OF A CONDENSATION AGENT AND THERMAL AND/OR PHOTOCHEMICAL POLYMERIZATION OF THE OBTAINED CONDENSATION PRODUCT | INSTITUT FUR NEUE MATERIALIEN GEMEINNUTZIGE GMBH (DE) | 2001-10-16 | — | — | US | disclosed |