SCHEMBL246606

SCHEMBL246606

C=C(C)C(=O)OCC(F)(F)C(F)(F)COC(=O)C(=C)C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
THRB P10828 1/20 0.45
ALDH1A1 P00352 2/20 0.42
HTT P42858 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18031805 0.94 TSHR (0.44) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL15435748 0.92 THRB (0.44) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL7562586 0.92 TSHR (0.42) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL246414 0.91 TSHR (0.45) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL36589 0.91 TSHR (0.45) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL246626 0.91 TSHR (0.45) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL15836491 0.90 TSHR (0.41) TSHRTHRBALDH1A1HTT
SCHEMBL248380 0.90 TSHR (0.44) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL246347 0.90 TSHR (0.44) TSHRTHRBALDH1A1HTTTDP1
SCHEMBL247163 0.90 TSHR (0.44) TSHRTHRBALDH1A1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12015122-B2 Silicon-based energy storage devices with carboxylic ether, carboxylic acid based salt, or acrylate electrolyte containing electrolyte additives ENEVATE CORPORATION (US) 2024-06-18 US claimed
US-20210218059-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH CARBOXYLIC ETHER, CARBOXYLIC ACID BASED SALT, OR ACRYLATE ELECTROLYTE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2021-07-15 US claimed
US-10816732-B2 Low dn/dT optical adhesives CORNING RESEARCH & DEVELOPMENT CORPORATION (US) 2020-10-27 US claimed
US-20200116946-A1 LOW DN/DT OPTICAL ADHESIVES CORNING RESEARCH & DEVELOPMENT CORPORATION 2020-04-16 US claimed
US-20190190070-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH CARBOXYLIC ETHER, CARBOXYLIC ACID BASED SALT, OR ACRYLATE ELECTROLYTE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2019-06-20 US claimed
US-10324260-B1 Optical assembly using low DN/DT optical adhesive CORNING RESEARCH & DEVELOPMENT CORPORATION (US) 2019-06-18 US claimed
WO-2019113528-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH CARBOXYLIC ETHER, CARBOXYLIC ACID BASED SALT, OR ACRYLATE ELECTROLYTE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2019-06-13 WO claimed
US-20240429448-A1 Silicon-Based Energy Storage Devices With Carboxylic Ether, Carboxylic Acid Based Salt, or Acrylate Electrolyte Containing Electrolyte Additives ENEVATE CORP (US) 2024-12-26 US disclosed
US-12015122-B2 Silicon-based energy storage devices with carboxylic ether, carboxylic acid based salt, or acrylate electrolyte containing electrolyte additives ENEVATE CORPORATION (US) 2024-06-18 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
EP-4249519-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. (US) 2023-09-27 EP disclosed
US-11649633-B2 Self-cleaning cool roof system U.S. SILICA COMPANY (US) 2023-05-16 US disclosed
US-20110026121-A1 Laminate, antireflective film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-7495037-B2 Dental coating materials IVOCLAR VIVADENT AG (LI) 2009-02-24 US disclosed
US-20080319104-A1 Hardening Dental Materials Featuring Adjustable Translucence IVOCLAR VIVADENT AG (LI) 2008-12-25 US disclosed
EP-1732499-A1 HARDENING DENTAL MATERIALS FEATURING ADJUSTABLE TRANSLUCENCE Ivoclar Vivadent AG (LI) 2006-12-20 EP disclosed
WO-2005097043-A1 HARDENING DENTAL MATERIALS FEATURING ADJUSTABLE TRANSLUCENCE IVOCLAR VIVADENT AG (DE) 2005-10-20 WO disclosed
US-20050165129-A1 Dental coating materials IVOCLAR VIVADENT AG (LI) 2005-07-28 US disclosed
EP-1510197-A1 Dental coating material Firma Ivoclar Vivadent AG (LI) 2005-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165129-A1 Dental coating materials PHOSPHO1, SPTAN1, ITGA1 TSHR 4370/4885THRB 3247/4885ALDH1A1 2568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.