Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042438 | 0.81 | SLC6A3 (0.57) | SLC6A3DRD2 | |
| SCHEMBL6042173 | 0.80 | MDM2 (0.45) | SLC6A3MDM2 | |
| SCHEMBL6953266 | 0.77 | SLC6A3 (0.41) | SLC6A3MDM2 | |
| SCHEMBL6951399 | 0.72 | SLC6A3 (0.37) | SLC6A3MDM2 | |
| SCHEMBL6041749 | 0.71 | SLC6A3 (0.42) | SLC6A3DRD2 | |
| SCHEMBL6042593 | 0.61 | SLC6A3 (0.37) | SLC6A3DRD2 | |
| SCHEMBL6041346 | 0.61 | CCR1 (0.37) | MDM2 | |
| SCHEMBL3827721 | 0.60 | SLC6A3 (1.00) | SLC6A3 | |
| SCHEMBL13679363 | 0.60 | SLC6A3 (1.00) | SLC6A3 | |
| SCHEMBL3827724 | 0.60 | SLC6A3 (1.00) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |