Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951399 | 0.85 | SLC6A3 (0.37) | SLC6A3MDM2 | |
| SCHEMBL6042173 | 0.81 | MDM2 (0.45) | SLC6A3MDM2 | |
| SCHEMBL6042438 | 0.78 | SLC6A3 (0.57) | SLC6A3 | |
| SCHEMBL6958920 | 0.78 | MDM2 (0.34) | SLC6A3MDM2 | |
| SCHEMBL7562710 | 0.77 | SLC6A3 (0.43) | SLC6A3MDM2 | |
| SCHEMBL6954522 | 0.72 | ESR2 (0.35) | — | |
| SCHEMBL6041749 | 0.69 | SLC6A3 (0.42) | SLC6A3 | |
| SCHEMBL7074672 | 0.67 | MDM2 (0.33) | MDM2 | |
| SCHEMBL6956483 | 0.67 | MAPT (0.35) | — | |
| SCHEMBL6042563 | 0.65 | CHRM2 (0.37) | SLC6A3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |