Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763900 | 0.82 | THRB (0.52) | THRBEPHX1ALDH1A1 | |
| SCHEMBL21821339 | 0.82 | THRB (0.52) | THRBEPHX1ALDH1A1 | |
| SCHEMBL113399 | 0.82 | THRB (0.52) | THRBEPHX1ALDH1A1 | |
| SCHEMBL27619935 | 0.79 | RXRA (0.43) | RXRARXRBRXRGFAAHEPHX1 | |
| SCHEMBL29681626 | 0.76 | RXRA (0.67) | RXRARXRBRXRGFAAHPTPN5 | |
| SCHEMBL611807 | 0.76 | RXRA (0.67) | RXRARXRBRXRGFAAHPTPN5 | |
| SCHEMBL5496140 | 0.76 | DPP4 (0.48) | RXRARXRBRXRGPTPN5CTSL | |
| SCHEMBL27259898 | 0.74 | RXRA (0.44) | RXRARXRBRXRGFAAHPTPN5 | |
| SCHEMBL14188565 | 0.74 | RXRA (0.65) | RXRARXRBRXRGFAAHPTPN5 | |
| SCHEMBL5865101 | 0.72 | RXRA (0.53) | RXRARXRBRXRGFAAHTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229012-A1 | PROCESS FOR PREPARING BETA-KETOESTER ACETAL | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2002-08-07 | — | — | EP | disclosed |