Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969017 | 0.86 | NPSR1 (0.76) | NPSR1LMNAALDH1A1ALOX15TSHR | |
| SCHEMBL10648951 | 0.86 | NPSR1 (0.75) | NPSR1LMNAALDH1A1GFERGAA | |
| SCHEMBL19586294 | 0.83 | NPSR1 (0.71) | NPSR1LMNAALDH1A1ALOX15TSHR | |
| SCHEMBL10650186 | 0.83 | NPSR1 (0.70) | NPSR1LMNAALDH1A1TSHRGAA | |
| SCHEMBL10650996 | 0.83 | NPSR1 (0.70) | NPSR1LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL10650837 | 0.83 | NPSR1 (0.70) | NPSR1LMNAALDH1A1TSHRMAPT | |
| SCHEMBL10651949 | 0.83 | LMNA (0.79) | NPSR1LMNAALDH1A1TSHRMAPT | |
| SCHEMBL12301766 | 0.82 | NPSR1 (0.69) | NPSR1LMNAALDH1A1ALOX15TSHR | |
| SCHEMBL10653275 | 0.82 | NPSR1 (0.69) | NPSR1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10651429 | 0.81 | NPSR1 (0.68) | NPSR1LMNAALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020499-A1 | PROCESS FOR THE PREPARATION OF 2-[3,4-DIHYDRO-1,4-BENZOTHIAZIN-4-YL]ETHYLMETHANE SULPHONATE | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-03-14 | — | — | WO | disclosed |
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |