Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650186 | 0.91 | NPSR1 (0.70) | NPSR1LMNAPOLBMAPTUSP2 | |
| SCHEMBL10652360 | 0.87 | NPSR1 (0.53) | NPSR1LMNAPOLBMAPTUSP2 | |
| SCHEMBL10651949 | 0.86 | LMNA (0.79) | NPSR1LMNAPOLBMAPTTDP1 | |
| SCHEMBL10649175 | 0.85 | NPSR1 (0.66) | NPSR1LMNAPOLBMAPTTDP1 | |
| SCHEMBL10653275 | 0.85 | NPSR1 (0.69) | NPSR1LMNAPOLBMAPTTDP1 | |
| SCHEMBL7562796 | 0.83 | NPSR1 (1.00) | NPSR1LMNAPOLBMAPTKMT2A | |
| SCHEMBL30808596 | 0.82 | ALDH1A1 (0.48) | NPSR1LMNAPOLBMAPTTP53 | |
| SCHEMBL10649933 | 0.82 | ALDH1A1 (0.48) | NPSR1LMNAPOLBMAPTTP53 | |
| SCHEMBL10651710 | 0.81 | NPSR1 (0.66) | NPSR1LMNAPOLBMAPTTDP1 | |
| SCHEMBL8264586 | 0.80 | NPSR1 (0.62) | NPSR1LMNAPOLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |