Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657402 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL15430918 | 0.84 | TSHR (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL40032 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL8395126 | 0.81 | TSHR (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28259378 | 0.81 | TSHR (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28552663 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Ammonia Solution, Strong SCHEMBL28794546 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Water SCHEMBL28203785 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL27722135 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL19820320 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242809-A1 | PHOTOCHROMIC HYDROXYURETHANE COMPOUND | TOKUYAMA CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| EP-2552996-B1 | ORGANOSILICONES | PROCTER & GAMBLE (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20170183452-A1 | ORGANOSILICONES | PROCTER & GAMBLE (US) | 2017-06-29 | — | — | US | disclosed |
| US-9650593-B2 | Organosilicones | THE PROCTER & GAMBLE COMPANY (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160060581-A1 | ORGANOSILICONES | PROCTER & GAMBLE (US) | 2016-03-03 | — | — | US | disclosed |
| US-9212338-B2 | Organosilicones | THE PROCTER & GAMBLE COMPANY (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150093350-A1 | ORGANOSILICONES | PROCTER & GAMBLE (US) | 2015-04-02 | — | — | US | disclosed |
| US-8940284-B2 | Organosilicones | THE PROCTER & GAMBLE COMPANY (US) | 2015-01-27 | — | — | US | disclosed |
| EP-2552996-A2 | ORGANOSILICONES | The Procter & Gamble Company (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20120052039-A1 | Organosilicones | THE PROCTER & GAMBLE COMPANY | 2012-03-01 | — | — | US | disclosed |
| WO-2011123727-A2 | ORGANOSILICONES | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110243878-A1 | ORGANOSILICONES | THE PROCTER & GAMBLE COMPANY | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150093350-A1 | ORGANOSILICONES | NISCH, XRCC6, RAD50 | SMN1; SMN2 221/4885ALDH1A1 2605/4885TDP1 658/4885 |
| US-20120052039-A1 | Organosilicones | NISCH, XRCC6, RAD50 | SMN1; SMN2 221/4885ALDH1A1 2605/4885TDP1 658/4885 |
| US-20110243878-A1 | ORGANOSILICONES | NISCH, XRCC6, RAD50 | SMN1; SMN2 221/4885ALDH1A1 2605/4885TDP1 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.