Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15430918 | 0.96 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL25523467 | 0.95 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13384514 | 0.93 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13002443 | 0.91 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL996238 | 0.91 | TSHR (0.48) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL14515640 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28259378 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15430925 | 0.89 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL733090 | 0.85 | ALDH1A1 (0.38) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL6841305 | 0.84 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639413-B2 | Polymerizable composition for optical materials and application of same | MITSUI CHEMICALS, INC. (JP) | 2023-05-02 | — | — | US | disclosed |
| US-20090145091-A1 | METHOD FOR TREATING OPHTHALMIC LENSES | CONNOLLY RICHARD | 2009-06-11 | — | — | US | disclosed |
| US-20090145086-A1 | METHOD FOR TREATING OPHTHALMIC LENSES | REYNOLDS GER M | 2009-06-11 | — | — | US | disclosed |
| US-20070122540-A1 | Coatings on ophthalmic lenses | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
| US-20070120279-A1 | Method for coating lens material | BAUSCH & LOMB INCORPORATED | 2007-05-31 | — | — | US | disclosed |
| EP-0619358-B1 | Photochromic composition | TOKUYAMA CORP (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5462698-A | Lenses | TOKUYAMA CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5395566-A | Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses | TOKUYAMA CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0619358-A1 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0559439-A2 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1993-09-08 | — | — | EP | disclosed |