Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749899 | 0.92 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL7452390 | 0.88 | MAPT (0.49) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL9202687 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL9364251 | 0.84 | MAPT (0.43) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL7563484 | 0.84 | MAPT (0.42) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL66269 | 0.83 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL30013512 | 0.83 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL29396197 | 0.83 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL7570836 | 0.83 | MAPT (0.42) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL21462144 | 0.83 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413911-B1 | REACTING A SULFONYL ISOCYANATE WITH A 2-AMINO-1,3,5-TRIAZINE OR 2-AMINOPYRIMIDINE, OR REACTING A SULFONAMIDE WITH A PHENYL CARBAMATE OR ISOCYANATE OF -1,3,5-TRIAZINE OR PYRIDINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | MAYER HORST (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6320046-B1 | A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-20 | — | — | US | disclosed |
| US-6043196-A | Herbicidal sulfonylureas, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | SLC5A1, DDT, SLC5A2 | MAPT 4842/4885ALDH1A1 1171/4885KDM4E 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.