Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.40 |
| ▸ | RXRG | P48443 | 15/20 | 0.40 |
| ▸ | RXRB | P28702 | 14/20 | 0.40 |
| ▸ | RARG | P13631 | 4/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562936 | 1.00 | RXRA (0.40) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7558942 | 0.85 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7558937 | 0.85 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7559490 | 0.83 | CYP26A1 (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7559493 | 0.83 | CYP26A1 (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7563931 | 0.78 | RXRA (0.39) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6478019 | 0.78 | RXRA (0.39) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6476670 | 0.77 | RXRA (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6476672 | 0.77 | RXRA (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7559807 | 0.73 | RXRA (0.36) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |