Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366363 | 0.83 | SIGMAR1 (0.50) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL29643326 | 0.83 | SIGMAR1 (0.50) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL173510 | 0.83 | SIGMAR1 (0.50) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL173511 | 0.83 | SIGMAR1 (0.50) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL29643341 | 0.83 | SIGMAR1 (0.50) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL1697074 | 0.82 | SMPD2 (0.48) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL4082840 | 0.82 | SMPD2 (0.48) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL6113113 | 0.81 | SMPD2 (0.47) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL6113112 | 0.81 | SMPD2 (0.47) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL6119288 | 0.81 | SMPD2 (0.47) | SMPD2SIGMAR1NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183249-A1 | Method of identifying inhibitors of CDC25 | TAYLOR NEIL R (AU) | 2002-12-05 | — | — | US | disclosed |
| WO-2002070680-A1 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| EP-1226237-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001027077-A2 | HYDROXYSULFONYLALKYLENE-, PHOSPHONOALKYLENE- OR DIFLUORO(PHOSPHONONON)METHYL- SUBSTITUTED BENZENE, OR BENZOFURAN DERIVATIVES AS NON-PEPTIDIC CDC25 INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2001016300-A2 | METHOD OF IDENTIFYING INHIBITORS OF CDC25 | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183249-A1 | Method of identifying inhibitors of CDC25 | CDC25C, CDC25A, CDC25B | SMPD2 354/4885SIGMAR1 4804/4885NR4A1 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.