SCHEMBL173511

SCHEMBL173511

CC(C(=O)O)N(C)c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.50
SMPD2 O60906 1/20 0.49
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
PPARG P37231 4/20 0.41
PPARA Q07869 4/20 0.41
AKR1B1 P15121 2/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
NCEH1 Q6PIU2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173510 1.00 SIGMAR1 (0.50) SIGMAR1SMPD2SLC6A2SLC6A4NR4A1
SCHEMBL7366363 1.00 SIGMAR1 (0.50) SIGMAR1SMPD2SLC6A2SLC6A4NR4A1
SCHEMBL29643326 1.00 SIGMAR1 (0.50) SIGMAR1SMPD2SLC6A2SLC6A4NR4A1
SCHEMBL29643341 1.00 SIGMAR1 (0.50) SIGMAR1SMPD2SLC6A2SLC6A4NR4A1
SCHEMBL8803002 0.85 SIGMAR1 (0.49) SIGMAR1SMPD2SLC6A2SLC6A4NCEH1
SCHEMBL7563347 0.83 SMPD2 (0.49) SIGMAR1SMPD2SLC6A2SLC6A4NR4A1
SCHEMBL29643295 0.83 SIGMAR1 (0.50) SIGMAR1SLC6A2SLC6A4NCEH1
SCHEMBL4082840 0.82 SMPD2 (0.48) SIGMAR1SMPD2NR4A1NR4A2NR4A3
SCHEMBL1697074 0.82 SMPD2 (0.48) SIGMAR1SMPD2NR4A1NR4A2NR4A3
Leucine SCHEMBL28593704 0.82 SLC7A5 (0.40) SIGMAR1SMPD2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026085582-A1 PROTEIN CAGES THE UNIVERSITY OF SYDNEY (AU) 2026-04-30 WO disclosed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-12605425-B2 TNF muteins and uses thereof OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2026-04-21 US disclosed
EP-4710935-A2 NOVEL IMMUNOTHERAPEUTIC COMPOSITION AND USES THEREOF Aravax Pty Ltd (AU) 2026-03-18 EP disclosed
EP-3980085-B1 COMPOSITIONS AND METHODS OF USING SAME FOR TISSUE REGENERATION UNIV RAMOT (IL) 2026-03-11 EP disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260049121-A1 SUPRAMOLECULAR HIGH AFFINITY PROTEIN-BINDING SYSTEM FOR PURIFICATION OF BIOMACROMOLECULES UNIV JOHNS HOPKINS (US) 2026-02-19 US disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-12466875-B2 Supramolecular high affinity protein-binding system for purification of biomacromolecules THE JOHNS HOPKINS UNIVERSITY (US) 2025-11-11 US disclosed
WO-1997035971-A1 A NOVEL MAMMALIAN GENE, bcl-w, BELONGS TO THE bcl-2 FAMILY OF APOPTOSIS-CONTROLLING GENES AMRAD OPERATIONS PTY. LTD. (AU) 1997-10-02 WO disclosed
WO-1997035887-A1 PRECURSORS OF CATALYTIC ANTIBODIES AMRAD OPERATIONS PTY. LTD. (AU) 1997-10-02 WO disclosed
WO-1997033614-A1 USE OF COXIELLA BACTERIA TO TREAT AUTOIMMUNE DISEASE THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1997-09-18 WO disclosed
WO-1997025344-A1 CLIP ANALOGUES AND AUTOIMMUNE DISEASE THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1997-07-17 WO disclosed
WO-1997023629-A1 A NOVEL RECEPTOR-TYPE TYROSINE KINASE AND USE THEREOF AMRAD OPERATIONS PTY. LTD. (AU) 1997-07-03 WO disclosed
WO-1997023501-A1 THERAPEUTIC COMPOSITIONS AMRAD OPERATIONS PTY. LTD. (AU) 1997-07-03 WO disclosed
WO-1997021727-A1 MYCOPLASMA RECOMBINANT POLYPEPTIDE VACCINES THE UNIVERSITY OF MELBOURNE (AU) 1997-06-19 WO disclosed
WO-1997015663-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-05-01 WO disclosed
WO-1997012037-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-04-03 WO disclosed
WO-1997004091-A1 NOVEL RECEPTOR LIGANDS AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605425-B2 TNF muteins and uses thereof TNFRSF1A, TNF, TNFSF11 SIGMAR1 1364/4885SMPD2 2716/4885SLC6A2 541/4885
US-20260049121-A1 SUPRAMOLECULAR HIGH AFFINITY PROTEIN-BINDING SYSTEM FOR PURIFICATION OF BIOMACROMOLECULES IL33, MAX, HM13 SIGMAR1 3563/4885SMPD2 3787/4885SLC6A2 4482/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A SIGMAR1 3294/4885SMPD2 675/4885SLC6A2 680/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A SIGMAR1 2289/4885SMPD2 998/4885SLC6A2 971/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B SIGMAR1 2401/4885SMPD2 453/4885SLC6A2 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.